A rare development opportunity awaits on Isle of Palms: a

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Lot For Sale

22 21st Avenue

Isle of Palms, South Carolina 29451

Charleston County

Community: Isle of Palms

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$1,850,000 0.320 acres

A rare development opportunity awaits on Isle of Palms: a buildable lot offered with plans in hand for a 5-bedroom, 5.5-bath home. Designed with both lifestyle and investment in mind, the proposed residence is ideal as a second home or short-term rental, featuring expansive open living spaces, en-suite baths, and an additional loft. The thoughtfully planned layout totals approximately 3,846 square feet. The homesite has been cleared while preserving grand oak trees and mature foliage, providing privacy in the front and lush natural landscaping in the rear. Perfectly located within easy walking distance to the beach and the popular restaurants and shops of Isle of Palms, this property offers the best of island living. Isle of Palms is a premier coastal community known for its miles ofpristine beaches, ocean views, and relaxed Lowcountry charm. With resort-style amenities and year-round recreationincluding golf, boating, watersports, and dining- it's the perfect setting for a vacation retreat or income-producing getaway.

  • Lot Size: 0.320 acre
  • Lot Dimensions: 
  • View Types: 
  • MLS #: 26004036
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Contact Information:
Beach Lot For Sale in Isle of Palms, South Carolina
Listing Agent: Anna Gruenloh, The Exchange Company, LLC., 843-224-6358, 843-224-6358 Listing Site, Listing Status: Active
Copyright © 2026 CHS Regional MLS. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.
Ad Number: 7263776
Viewed 28 times.
Updated: Feb 12, 2026

This property is a Lot located at 22 21st Avenue, Isle of Palms, South Carolina 29451, and is currently For Sale at $1,850,000.